Fig. 8. Plasma insulin levels in oc/oc mice. Blood samples were collected from (A) natural-feeding (with a lactating mother and a chew diet) wild-type (+/+; n=7), heterozygous (oc/+; n=8) and oc/oc (n=7) mice, or (B) fasting (without a lactating mother or a chew diet) mice loaded with glucose [wild-type (+/+; n=10), heterozygous (oc/+; n=10), and oc/oc (n=10)] or saline [wild-type (+/+; n=7), heterozygous (oc/+; n=7), and oc/oc (n=3)] (B). Plasma insulin contents were measured by ELISA. (C) The blood glucose levels before (open bar) or after (solid bar) oral administration. The results are presented as means ± s.d. *P<0.05, compared with wild-type mice; **P<0.001, compared with wild-type mice.