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Figure 1


Fig. 1. Schematic representation of podoplanin fusion constructs used for transfection. Numbers indicate podoplanin amino acid sequences (Martín-Villar et al., 2005) conserved in the construct. CT, cytoplasmic domain; EC, ectodomain; FP, fluorescent protein (EYFP or EGFP) used for the experiments specified in the text; SP, signal peptide; TM, transmembrane domain. Basic amino acids (bold) within the CT domain were substituted by uncharged polar residues (bold and underlined).