Fig. 6. ssh suppression of the activated Sev pathway. (A) Rough eye phenotype due to the sevS11 construct (sev-Gal4 sevS11/+). (B) Suppression of the sevS11 rough eye phenotype when UAS-RNAi-ssh is activated (UAS-RNAi-ssh/+; sev-Gal4 sevS11/+). (C) The activation of the transgene (UAS-RNAi-ssh/+; sevGal4) does not alter eye morphology. Upper panels: SEM images. Lower panels: tangential semi-thin sections with R7 photoreceptors colored green. (D) The histogram shows distribution profiles of the number of R7 photoreceptors per ommatidium for each genotype represented. The statistical analysis reveals significant differences between the genotypes (P<0.001).