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Figure 4


Fig. 4. Internalised EGF is trafficked in rapidly moving PtdIns4KII{alpha}-containing vesicles. Time-lapse images were obtained from live HT1080 GFP-PtdIns4KII{alpha} cells that had been serum-starved and stimulated with Rh-EGF for 120 seconds. Frames from the boxed region show the movement of a single vesicle marked with an arrow. Also see supplementary material Movie 2. Bar, 10 µm.