Fig. 4. Dermal fibroblasts were plated onto collagen-coated glass coverslips in FM as described and pre-treated with 10 µM PP2 for 6 hours at 37°C. The migration of each single cell was monitored over a 1-hour period in FM in the presence or absence of 1 µM ß-AR agonist, as described. The speed and distance traveled are represented graphically in A and B, respectively. The data are representative of three independent experiments with three different fibroblast strains (n=50). Values plotted are means ± s.e.m. ^*P<0.01 between ß-AR agonist and controls.