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Figure 3


Fig. 3. Regulation of phagocytosis and macropinocytosis by PI 3-kinases. The involvement of PtdIns(3,4,5)P3 effectors in macropinocytosis (left) and phagocytosis (right) are indicated in red. PtdIns(3)P effectors needed for macropinocytosis or phagosome maturation are indicated in blue. Arrow thickness corresponds to the magnitude of various trafficking pathways indicated.