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Figure 4


Fig. 4. EM analysis of the LH mutant newborn skin. The BM of the homozygous (m/m) newborn skin showed thinner lamina densa (B, arrows) than wild-type (+/+) littermates (A). The structure of collagen bundles was looser and less organized in the homozygotes (D,F) than in the wild type (C,E). Collagen fibrils in the homozygotes were covered with diffuse material (* in D and F). Bars, 0.2 µm.