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Figure 11


Fig. 11. Schematic representation of the positioning of PKCs, Src and Cdc42 in the signalling cascade leading to podosome assembly in HUVECs in response to PMA. Asterisks indicate podosome inducers in endothelial cells. PKC{delta} is involved in PMA-induced podosome formation in HUVECs but its exact role and position in the cascade remains to be elucidated.