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Figure 8


Fig. 8. Effects of Wnt signalling on human osteoclast formation and activity. Wnt3a (10-100 ng/ml) had no effect on the formation of TRAP-positive multinucleated osteoclasts generated from peripheral blood mononuclear cells cultured in the presence of RANKL and M-CSF (open bars) and had no effect on their resorptive activity (closed bars). Data are mean ± s.e.m., n=5.