Fig. 2. Blocking ß1 integrin function induces differentiation. (A) Dot plots of PAP expression following blocking with anti-ß1-integrin antibody. Controls were set at 3%. (B) Bar chart summarising the effect of blocking ß1 integrin on the expression of differentiation markers. Data are mean ± s.e.m. of three experiments. (C) Expression of differentiation markers CK18, PAP and AR (FITC/green) in
2ß1hi cells treated with ß1-blocking antibody. Cells were counterstained with the nuclear stain DAPI (blue).