Fig. 6. Ionomycin can trigger redistribution of
II spectrin but lacks a reversible mechanism.
II spectrin redistributes into the bleb ends (arrows) upon an application of ionomycin. After ionomycin-induced membrane blebbing,
II spectrin loses its assembly at the membrane skeleton and diffuses into the cytosol (arrowheads). For the live image of this cell, see supplementary material Movie 2. Bar, 10 µm.