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Figure 6


Fig. 6. Ionomycin can trigger redistribution of {alpha}II spectrin but lacks a reversible mechanism. {alpha}II spectrin redistributes into the bleb ends (arrows) upon an application of ionomycin. After ionomycin-induced membrane blebbing, {alpha}II spectrin loses its assembly at the membrane skeleton and diffuses into the cytosol (arrowheads). For the live image of this cell, see supplementary material Movie 2. Bar, 10 µm.