Fig. 2. Dose-dependent effect of profilin IWT on PC12 cell differentiation. The percentage of differentiated cells 76 hours after the addition of NGF, is shown as a function of the overexpression level of human profilin IWT. The cells were scored as differentiated when they had at least one neurite that is longer than the cell diameter. Results are presented as means ± s.e.m. with n=177-278 cells.