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Figure 3


Fig. 3. Graph representing cytochrome reduction and inhibition of VO2 in induced Tet-iNOS 293 cells upon addition of 0 µM (blue), 1 µM (red), 2.5 µM (green), 5 µM (magenta) and 10 µM (cyan) L-arginine, and 0 µM (teal) and 2.5 µM (gold) L-arginine in the presence of 500 µM S-EITU (n=6 for each group). Left and right sides of bars indicate [O2] at which significant (P<0.001) changes from baseline values occur in cytochromes aa3 and VO2, respectively. Arrow indicates addition of L-arginine at 71.3±3.4 µM O2 (n=30).