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Figure 5


Fig. 5. Mlp84B and D-titin colocalize at the Z-disc and have similar mutant phenotypes. (A) Distribution of Mlp84B and {alpha}-actinin at the Z-disc of somatic body wall muscle; bar, 10 µm. Enlargements of two Z-bands are shown below the larger micrograph. (B) Diagram of the relative positions of Mlp84B, actin, {alpha}-actinin and D-titin in the Z-disc. (C) Colocalization of Mlp84B and D-titin in somatic muscle Z-disc; bar, 10 µm. Enlargements of two Z-bands are shown below the larger micrograph. (D) Representative pupal cases; bar, 200 µm. (E) Average axial ratios for pupae of indicated genotype (*P>10–6, comparing mutant to w1118).