Fig. 7. Effect of p53 deficiency on intracellular ROS level in SiHa cells undergoing oxidative stress. (A) ROS levels in untreated and H₂O₂-treated (12 hours) SiHa and SiHa cells with p53 inhibited with siRNA, as detected by FACS after CM-H₂DCFCA-staining. (B) ROS levels were expressed as the mean ± s.d. intensity of cell fluorescence. ^*P<0.001 compared to the corresponding negative control by Student's t-test.