Fig. 7. MLN51-overexpressing breast tumours contain cytoplasmic foci resembling SGs. (A) Immunohistochemical analysis of MLN51 subcellular localization in two ductal carcinomas. In cancer cells, MLN51 staining is either diffuse in the cytoplasm (a) or appears in punctate cytoplasmic structures (b). Sections are counterstained with Haematoxylin (nuclei are violet). (B) MLN51-expressing tumours were double-stained for MLN51 (green) and FMRP (red) or with MLN51 (green) and PABP (red). Nuclei were counterstained with Hoechst (blue). Note that both FMRP and PABP are present in cytoplasmic foci positive for MLN51. Bar, 10 µm.