(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 8


Fig. 8. Spindle checkpoint activation by cytochrome oxidase inhibitor. gEGFP-Mps1 embryos were incubated in either absence (–CN) or presence (+CN) of cyanide for 5 (A) or 15 (B) minutes before fixation and labeling with anti-{alpha}-tubulin (Tub) and a DNA stain (DNA). Cyanide induces reorganization of EGFP-Mps1 (Mps1), microtubules and chromatin during metaphase (A) and interphase (B) that is indistinguishable from the effects of anoxia. Bar, 5 µm.