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Figure 8


Fig. 8. Cartoon highlighting results from the studies using integrin-function-blocking antibody. PM, plasma membrane; N,nucleus; {alpha}vbeta, integrin heterodimers that contain the {alpha}v subunit, are expressed in keratinocytes and include integrins {alpha}vbeta5, {alpha}vbeta6 and {alpha}vbeta8; {alpha}beta1, integrin heterodimers that contain the beta1 subunit, are expressed in keratinocytes and include integrins {alpha}2beta1, {alpha}3beta1 and {alpha}5beta1 (see supplementary material Fig. S1 for expression profiles of total keratinocyte integrins and Fig. 6B for surface integrins).