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Figure 9


Fig. 9. NS-398 treatment causes neutrophil arrest in hi2217;MPO:GFP embryos. (A) Mutant hi2217;MPO:GFP embryo tailfin following treatment for 1 hour in 250 µM NS-398. Fluorescence image of the first frame from Movie 3 in supplementary material overlaid onto corresponding OCC image; dashed line indicates the location of the vasculature. (B) Cell tracks of neutrophils from embryo in A, kept in the presence of NS-398. (C) Tracks from same embryo as in A and B, 1 hour after washing out the drug. Average displacements for each set of tracks are indicated in the lower left corner of B and C.