Fig. 2. Distribution of HP1
and HP1
in human lymph nodes. (A) Schematic representation of lymph node structure. (B) Double staining for HP1
or HP1
(brown) and B- (CD20) or T-cell (CD4 and CD8) markers (red). (C) Expression of HP1
and HP1
in primary (pf) and secondary follicles comprising a germinal center (GC) and a mantle zone (mz). The area of primary follicles is indicated by dots. (D) Detection of HP1
, HP1
, Ki-67 and me2K4-H3 in the B- and T-zone.