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Figure 3


Fig. 3. Formation and migration of endocrine cells. (A) Single somatostatin-positive cell in the duct epithelium. (B) Typical cluster showing SS- and insulin-positive cells. (C,D) Triple-stained large endocrine cell clusters: (C) insulin (green), SS (red), glucagon (blue); (D) insulin (green), PP (red), glucagon (blue). Bars, 20 µm. (E) Hypothetical mechanism for endocrine cell formation from duct epithelium.