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Figure 4


Fig. 4. Effects of LPR1 on filopodia are not mediated by the small GTPase cdc42. (A) HeLa cells were transfected with vectors for expression of myc-tagged cdc42Q 61L or cdc42T 17N. HeLa cells were transfected with vectors for expression of EGFP-LPR1 and myc-tagged constructs of cdc42T 17N (B), Wasp-CRIB (C) and Scar-WA (D). In all cases, EGFP- and myc-tagged proteins and actin organization were visualized by fluorescence microscopy. Bars, 10 µm.