Fig. 6. N18-GFP-HASPB-induced plasma membrane blebbing correlates with enhanced cell invasion in 3D matrices. Cell migration across matrigel-coated transwells was assessed after 48 hours and invasiveness was calculated relative to GFP-expressing cells. Values are the arithmetic means of three independent experiments performed as duplicates with the indicated s.e.m. Statistical significance for the values obtained with HASPB-GFP-expressing cells was evaluated by Student's t-test relative to GFP-expressing cells (N18-HASPB-GFP P=0.019, N18-myr-HASPB P=0.7).