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Figure 4


Fig. 4. LN rigidity response is RPTP{alpha} independent in neurons. (A) Axon differentiation is inhibited by increasing rigidities of LN-coated substrates in both control and knockout neurons. (B) Neurite extesion is stimulated by soft LN-coated substrates, and loss of RPTP{alpha} had no effect on this behavior. The results (mean ± s.e.) were statistically significant (P<0.01).