JCS -- Hayashida et al. 120 (23): 4230 Figure IG9

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Fig. 9. ECM accumulation and Smad phosphorylation and FAK phosphorylation in kidneys of bleomycin-treated mice. (A) Protein lysate from frozen kidney samples of bleomycin-treated (bleo) or control mice were analyzed for expression of type I collagen and Smad3 phosphorylation by immunoblotting. Representative results from two animals are shown. (B) Immunofluorescent staining of renal cortex sections for phospho-Y397 FAK (top panels) and FAK (bottom panels) is shown. DAPI staining (blue) for nuclei is also shown to locate glomeruli in the upper panels.