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Figure 5


Fig. 5. Inv-Dsg2 transgenic mice show hyperproliferative epidermis and increase in mitotic activity. Paraffin embedded sections of adult wild-type (A,C) and Inv-Dsg2 transgenic (B,D) skin were stained with antibodies to detect either PCNA expression (A,B) or BrdU incorporation (C,D; green). Insets show higher resolution images. Also shown in red in C and D is immunostaining for CK14.