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Figure 3


Fig. 3. Laminin activates JNK in C2 myotubes. (A) JNK activation by laminin was observed in differentiated C2 myotubes but not in undifferentiated myoblasts. (B) The time course of laminin stimulation of c-Jun phosphorylation in myotubes shows a transient response to laminin that results in c-Jun phosphorylation that reaches a maximum within 15 minutes and subsequently declines to baseline levels by 60 minutes.