Fig. 6. (A-I) Time-lapse imaging of apoptotic progression in control S2 cells (A-C), HADnr1-expressing S2 cells (D-F) and HADnr1C563Y-expressing S2 cells (G-I). All cell lines were treated with dIAP1 dsRNA and imaged at the indicated time. Whereas DIAP1 depletion induces rapid apoptosis in control S2 cells, overexpression of Dnr1 or Dnr1C563Y suppresses the loss of DIAP1 phenotype.