Fig. 6. (A) Effect of OOX and FSH (100 ng/ml) on levels of mural transcripts in cumulus cells treated for 12 hours. Effect of SB431542 (10 µM) (B) or SIS3 (20 µM) (C) alone or in combination with FSH (100 ng/ml) on levels of mural transcripts in COCs cultured for 15 hours. Transcripts were measured by real-time PCR and normalized to Rpl19 mRNA. abcP<0.05, significant differences.