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Figure 3


Fig. 3. Embryonic development from eggs lacking T-synthase. (A) T-syn–/– embryos were obtained from mating T-synF/F:ZP3Cre females to T-syn+/– males. At E12.5 mutant embryos exhibited angiogenic defects with hemorrhaging in the spinal and brain area (open arrowheads). (B) Embryos of each genotype were generated in approximately equal proportions from T-syn–/– eggs.