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Figure 7


Fig. 7. Epidermal proliferation and differentiation appears normal in KO epidermis. Skins from day-4 WT (A,C,E,G,I,K) and KO (B,D,F,H,J,L) mice were fixed, sectioned and stained with antibodies and with phalloidin to label F-actin. Colour codings correspond to the secondary antibodies or phalloidin used in each case. Note the increased KO epidermal thickness. Inset, higher-magnification of the boxed area. {alpha}6β4, {alpha}6β4 integrin; β1, β1 integrin; phall, phalloidin; Ker14, Keratin 14; Ker1, Keratin 1; Ker10, Keratin 10; E-Cad, E-cadherin; epi, epidermis; de, dermis; hf, hair follicle. Scale bars: 10 µm.