Fig. 2. Immunoelectron microscopic analyses indicate the localization of β-synemin along IFs and in costameres. (A,B) Gold particles labeling β-synemin (arrowheads) were distributed along IFs and on subsarcolemmal dense plaques overlying Z-lines, or costameres. (C) A thin thread (arrow), possibly plectin molecules, projects from IF to a dense plaque labeled with gold particles. Bars, 0.1 µm.