Fig. 9. Immunoblots of costameric, IF-associated and IF proteins from wild-type (N) and dystrophin-deficient (A) mdx mice (5-6 weeks old) and CXMDJ dogs (6-10 months old). (A,B) Reduced expression of -dystrobrevin 1, -dystrobrevin 2 and -dystrobrevin 3, and increased expression of utrophin, integrin β1d, metavinculin and vimentin were detected in dystrophin-deficient mice and dogs when compared with wild-type controls. Note slightly elevated expression of plectin and β-synemin in dystrophin-deficient dogs. Values represent the mean ± s.d. (error bars) of muscle specimens obtained from three mice and dogs. ^**P<0.01 and ^*P<0.05, compared with control mice or dogs.