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Figure 3


Fig. 3. Meiotic divisions in the wild type (A-C), and in hop2A{Delta} (D-F) and spo11{Delta} (G-I) mutants. (A) In wild type, five bivalents can be discriminated in diakinesis or metaphase I. In anaphase I (B) and anaphase II (C), equal amounts of chromatin are segregated. In mutant meioses, chromosomes appear to be unpaired (D,G) and anaphase I is often clearly asymmetric (E,H) with a large (large arrow) and a small (small arrow) number of chromosomes. (F,I) Correspondingly, asymmetric anaphase II configurations with large numbers of chromatids (large arrowheads) and small numbers of chromatids (small arrowheads) occur in the mutants. Notably, chromosome fragments are absent in hop2A{Delta} meioses. Scale bar: 10 µm.