Fig. 2. Glucolipotoxicity in human islets. Human islets were cultured for 72 hours or 6 days in the presence or absence of oleate (gray bars) or palmitate (black bars) at a glucose concentration of 6.1 or 28 mM, as indicated. The results are the means ± s.e.m. of four to seven independent experiments. ^*P<0.05, ^**P<0.01 vs respective control.