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Figure 6


Fig. 6. Repair of DNA double-strand breaks is impaired without an intact central element. Meiotic chromosomes in wild-type and Tex12–/– E17.5 oocytes immunolabeled for STAG3 (axial elements, green) and {gamma}-H2AX (red) or BRCA1 (red). Centromeres are labeled with CREST (white). Bar: 5 µm.