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Figure 2


Fig. 2. Villus coalescence in adult KO/Tg distal small intestine. (A-D) Whole-mount views of distal small intestine mucosa. Compared with the villi of Het/Tg mice (A), the KO/Tg villi (B-D) showed varying degrees of villus coalescence, from a widened phenotype (B) to a `cerebroid' pattern (C) to a `mosaic' pattern (D). (E-G) Scanning electron micrographs confirmed the findings in (A-D). Bars, 200 µm.