JCS -- Iyadurai et al. 121 (16): 2643 Figure IG8

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Fig. 8. Increased levels of secreted Spitz suppress the rough eye phenotype. The rough eye caused by transgenic expression of a truncated Glued product is suppressed by sSpitz overexpression. (A) When the ${Delta}$ Gl transgene is driven by two copies of an actin-GAL4 driver, a rough-eye phenotype results. (B) The ${Delta}$ Gl phenotype is significantly suppressed by coexpression of the secreted form of Spitz protein from a UAS-sSpitz transgene. Genotypes shown: (A) UASp- ${Delta}$ Gl, act5c-GAL4/CyO; act5c-GAL4/+, and (B) UAS-sSpitz/UASp- ${Delta}$ Gl, act5c-GAL4; act5c-GAL4/+.