Fig. 1. Fibrillin-1 microfibril assembly by human dermal fibroblasts. (A) Representative confocal microscopy images of the assembly of microfibrils (using rabbit anti-proline-rich region pAb; red) and fibronectin (FN) (using FN-3E2 mAb to cellular fibronectin; green) by HDFs at 24 hours and 5 days. Cell nuclei were stained with DAPI (blue). Scale bars: 50 µm. (B) Enlarged images from A. These experiments were repeated several times with similar results.