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Figure 1


Fig. 1. Diagram showing the topology of the connexin polypeptide relative to the membrane (top) and the amino acid sequences of the N-terminal domains of wild-type CX37 and the deletion or substitution mutants (bottom). NT, amino terminal domain; CL, cytoplasmic loop; CT, C-terminal domain; TM1-TM4, transmembrane domains 1-4; E1 and E2, extracellular loops.