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Figure 8


Fig. 8. Intensive activity at axons induces inverse changes in axonal and somatic excitability. (A) Axonal HFA lowers threshold stimuli at axons (TSAx, bullet) and raises threshold stimuli at cell bodies (TSCB, {circ}; n=10). (B) Axonal HFA increases TSAx (filled symbols) and decreases TSCB (open symbols; n=9). (C) Single spikes elicited by threshold stimuli (50% probability of spike firing) at axons (right) and soma (left) before (blue traces) and after HFA (red traces). TSCB rises and TSAx is reduced after axonal HFA.