Fig. 1. (A) Schematic of the genetic cross to screen for mutations in the Pax6 deletion interval. Mutagenized males are crossed with females carrying the Pax6^Sey-Neu small-eye point mutation. Small-eye offspring (a fraction of which will be carrying a novel point mutation in the region) are crossed with mice carrying the Pax6^Sey-1H deletion. The four resultant genotypes are shown below. ENU, ethylnitrosourea. (B) Gene content in the region that is encompassed by the Pax6^Sey-1H deletion.