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Figure 2


Fig. 2. The RRR motif retains the protein in the ER. The maturation state of the indicated proteins in cell lysates of transfected COS-7 cells was examined by Endo H digestion. Representative immunoblots (IB) for the Myc tag show the mature (black arrowheads) and immature (open arrowheads) forms of the proteins. The experiments were repeated at least three times.