Fig. 5. Summary of transcriptome analysis and results. Inhibition of either pea3 or erm induces significant changes in the cellular transcriptome of MMT cells. Expression levels of mRNAs from pea3 or erm siRNA-treated cells were individually compared with control oligonucleotide-treated MMT samples by genome-wide microarray analysis. The absolute number of probes detecting statistically significant up- or downregulation following inhibition of either of the two Ets factors is shown to the left of each bar; the maximum positive or negative logarithmic (base two) fold-change is shown to the right. The black to gray gradient indicates positive, and the white to gray gradient negative fold changes in expression. The subset of genes regulated in both cases is also shown ().