Fig. 4. Effect of activation of M on their proliferation. Changes in cell density relative to the initial density are shown in A, and BrdU incorporation into DNA after 12 hours activation and 4 hours incubation with BrdU are shown in B. Activation led to complete arrest of cell proliferation that could be partially reversed by treatment with SEITU. ^*, Significantly different from values in non-activated cells; , Significantly different from IFN + LPS-treated cells (P<0.05, ANOVA, Tukey's test). Results are mean±s.d., n=5.