Fig. 9. Diagram summarising the role of the flagellum in flagellar pocket formation. (A) General view of the monoflagellated trypanosome cell where the flagellar pocket area has been made transparent to visualise flagellar pocket associated components. For simplicity, only the main organelles studied in this work have been represented. (B-D) Situation in wild-type cells with one flagellum (B), one old and one new flagellum prior to microtubule assembly (C) and after flagellar pocket duplication (D). (E) Situation in a nonflagellated cell where anterograde IFT was inhibited. (F) Situation in a cell where a short flagellum has been produced upon blockage of retrograde transport. The internal region of the emerging flagellum is also shown. See text for details.