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Figure 7


Fig. 7. Phosphorylation of FAK tyrosine 397 in hippocampal neurons after the inhibition of P2X7 receptors. (A) Growth cones of control or BBG-treated cultured hippocampal neurons stained with an anti-FAK antibody. Scale bar: 10 µm. (B,C) Western blots of FAK, FAKS843-P and FAKY397-P in hippocampal neurons treated with BBG (5 µM) for 30 or 60 minutes. Actin was used as a loading control and the graphs represent the mean ± s.d. of FAK, FAK-P and the FAK-P:FAK ratio from three different experiments (*P<0.05, paired t-test).