Fig. 1. Vimentin expression constructs and eye phenotype. (A) Schematic representation of the constructs used for expression of wildtype, R₁₁₃C point-mutant (VimR₁₁₃C) and C-terminal truncated (VimC2B) vimentin transgene. All constructs are based on the mouse vimentin gene with its own regulatory elements. (B) Note turbid lens in a 22-week-old animal expressing the VimR₁₁₃C mutant (arrow).