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Figure 2


Fig. 2. NMJ-capping cells are not Schwann cells but express collagen-synthesising enzyme and neuregulin. (A) Confocal projection images of a TS muscle endplate in an S100-eGFP transgenic mouse, showing endogenous fluorescence in terminal Schwann cells (green) overlying endplate ACh receptors (blue). The right panel shows superimposition of 2166 immunostaining (red). (B) Immunostaining for the collagen-synthesising enzyme rPH of an NMJ-capping cell in rat TS muscle. (C) Immunostaining of a NMJ-capping cell in mouse triangularis sterni muscle using HM-24 antibody, which recognises GGFII/neuregulin. Scale bar: 50 µm.