Fig. 1. Skin wound healing is delayed in uPAR-KO mice. uPAR-wt and -KO skins were wounded, and cross-sections of skin samples were collected 3, 5 and 11 days later. (A) Representative wt and uPAR-KO cross-sections of 5-day-old wounds stained for keratin 5 (K5) are shown. Arrows indicate the position of the advancing epithelial edges and the wound diameter. Below the arrows are reported the mean wound diameters 5 days after injury. (B) Average wound diameters (± s.d.) from 10 wt and 13 KO mice for each time point (Student's t-test).